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Dimetapp, Childrens Non-Drowsy Allergy ODT e Alimento

Resultado da verificação da interação do medicamento Dimetapp, Childrens Non-Drowsy Allergy ODT e Alimento quanto a segurança do uso em conjunto.

Resultado da verificação:
Dimetapp, Childrens Non-Drowsy Allergy ODT <> Alimento
Relevância: 03.07.2019 Revisor: Shkutko P.M., M.D., in

Na verificação da interação, conforme informações das fontes confiáveis como Drugs.com, Rxlist.com, Webmd.com, Medscape.com, foram identificadas as contra-indicações ou efeitos colaterais que podem prejudicar a saúde ou aumentar o efeito negativo no uso do medicamento em combinação com alimento ou estilo de vida.

Consumidor:

Informação ao consumidor para que este menor interação não está disponível no momento. Algumas pequenas interações medicamentosas podem não ser clinicamente relevante em todos os pacientes. Menor interações medicamentosas não costumam causar danos ou exigir uma mudança na terapia. No entanto, o seu médico pode determinar se os ajustes para os seus medicamentos são necessários.

Profissional:

Teoricamente, o sumo de toranja pode aumentar as concentrações plasmáticas de loratadina, como faz com outros fármacos que são substratos do CYP450 3A4 enzimática caminho. O mecanismo proposto é a inibição da CYP450 3A4 mediada metabolismo de primeira passagem na parede do intestino por certos compostos presentes em toranjas. O significado clínico deste potencial de interação é desconhecido. Relatadas interações com potente CYP450 3A4 inibidores como claritromicina, eritromicina e cetoconazol produziram aumentos substanciais na área da concentração plasmática-tempo de curva (AUC) da loratadina e do seu metabólito ativo, descarboethoxyloratadine, sem associada a alterações no perfil de segurança global da droga.

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Dimetapp, Childrens Non-Drowsy Allergy ODT

Nome genérico: loratadine

Marca comercial: Alavert, Claritin, Claritin Reditab, Clear-Atadine, Dimetapp ND, Ohm Allergy Relief, QlearQuil All Day & Night, Tavist ND, Wal-itin

Sinônimos: Dimetapp ND

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